This is the roadmap for FreeDiams. It can be also concidered as a part of the changelog between main stable versions.

Where possible, kindly avoid multiple small edits.

• This page includes an outline for the next version of FreeDiams. Lengthy text (> 1-2 lines) is best replaced by a link elsewhere.

• in app
  • (placeholder)
• deciding on managing uniqueness of drugs - see post
• licensing: what to do about option for free license for CA drug files?
  • Sent registration form (may 2010) for the Ca DB but still no response…
• idea development for Standardized Protocols (SPs)
• ability to send (directly from the application) to the community server drugs interactions or comments on interactions directly on our website or on a bugzilla website.

• Merged all drugs database sources and DDI into one big database
• Drugs have a persistent in time surrogate private key
• Adding warnDuplicates in ATC table
• Using routes in most drugs sources (Fr, Ca, Us, Be)
• Routes are ID time persistent

• in the schema
  • change “Dosages” to “Strength”
• split and store separately strength and units?
• see drug strength storage in db (#2 line 4 in) this post
• Make DRUGS.TYPE_MP and DRUGS.AUTHORIZATION varchar(40) and add to tooltips under UID_label: <UID>; <ATC> with labels defined in the INFORMATIONS table?

• Lowering class and inn duplication according to DDI database data (editable in FreeToolBox)
• Updating drug-drug interactions to the AFSSAPS 10/2011 data
• Removing all duplicated non usefull DDI

• Started an experimental PIM engine (Beers criteria 2003 non related to diagnosis or conditions)

• HUMIRA and corticosteroids and immunosuppressants (methotrexate)

• New drug engine manager
• Rewrote DDI engine, Allergy engine
• First experimental drug engine for PIMs
• Fully updated Interaction Synthesis Dialog (with bibliography)
• Update translations

• In Debian/Ubuntu see output of

  lintian -i -I *.dsc *.deb

• In protocol window clicking on ProtocolView Remove button → removes ALL protocols
• Re-order the daily schemes ?
• Add version N° to transmitted dosage
• Add an automatic “missing DDI” reporter (for users with internet connection)
• Update documentation
• Add a form to review FreeDiams and send to the dev list when FreeDiams is used more than 100 times
• Describe plan for how to contribute interactions
• Manage : click in file navigator on a *.di file –> opens FreeDiams and load the file
• Manage : Drag a *.di file on a FreeDiams instance –> opens the file
• Manage biological datas units switching (related project
• Put applications params into the user database when the MySQL server is activated
• Automatic management of plurials forms for periods in prescriptions
• Add proxy params for the updatechecker and the messagesender objects
• support for combo search (text search catches both commercial and molecules)
• when dropping templates : need to check/know which database to use, and check validity of drugs
• inform user if opened prescription contains no-longer-commercialized drugs
• re-write documentation for Available personal protocols
• update patient available tokens
• add an undo function in daily scheme widget
• Templates → add print, save and quit if used with an external EMR ?
• Add a dialog for users who want to share : Templates or Protocols (need a sender and an document integrator)
• when changing font size of template view → change the font without need to restart app
• extend search molecules wildcards to apply also to form, strength
• Manage the XML value in `FreeDiams_In version=xxx` ?
• Copy/paste bug in Qt when used with MacOs.
• support for combo search (text search catches both commercial and molecules)
• support for decimal ”.” not just ”,” … this is not just a database question but pertains also to Creatinine (mg/l)
• toolbar icon for limitations: maybe replace “clock” with “hourglass” as better communicating that “time is running out”?
• management of sequential prescription (1/2cp day one, 1cp day two…)
• In order to simplify interactions testings :
  • make FreeDiams able to read an XML file and check founded interactions
    • XML Schema :
    • <InteractionTest expected=“true/false”>
      • <Atc code=”” OR label=””>
      • <Atc code=”” OR label=””>
    • </InteractionTest>
  • create a report of tested interactions in a table
• Create a total interaction score. Before saving/printing if score > MaxScore –> alert user of the interactions.
• in Preferences > Drugs > Selector add columns
  • TYPE_MP (or Marketing Permission?)
  • Authorization
• CLI
  • support for (see this post)
  • fertility state information
  • lactation
  • takes alcohol
• generic prescribing (save prescription XML without requiring a company drug UID)
• make GUI “controllably visible” any parameterized patient details? see this post
• consider to replace toolbar icon for limitations “clock” with “hourglass” as better communicating that “time is running out”?
• can FD by default (or Preference) suppress display of uncommercialised drugs?
• prepare adverse effects database : link ATC codes to known adverses effects, create a search engine.
• In print dialog: allow to include / exclude specific tokens (like clinical data : allergies, pregnant, lactation, renal function, creatinine clearance etc)
• prepare a XML encoded file for:
  • chronic renal failure and ATC dosages or contra-indications
  • idem for lactation and pregnancy
  • idem for elderly and pediatrics
• Integrates probably inappropriate drugs in elderly:
  • Pricus datas in german
  • Priscus english publication
  • French list
  • Mixte Ca/Us
  • US experts
  • Beers list
  • Beers list 2003 update: Arch Intern Med. 2003;163:2716-2724.
  • Ca
• Add a tag in the IAM tree for duplicates screening in the FreeDiams IA engine (eg: cyp substrats==no duplicate screening)
• Sync from USB
  • http://groups.google.ca/group/freemedforms/msg/a47555978eb767c9
• Create a new XML Tag exchangeIn file : <EMRPDFCache value=“yes/no” path=”/abs/path/to/store/and/return/files.pdf”/> ???
• Add in drugs database schema the AE_REPORT_URL to ease the reporting of adverse effects
• GNUmed specific dev:

  Now that I've consolidated the GNUmed FreeDiams API I'd like 
  to further develop it. The two use cases I would want to 
  cover next are: 
  1) pass a list of drugs to FreeDiams and tell FreeDiams 
          "show me what you think about the combination of these drugs in a patient" 
          Ideally, the information could be passed back to the 
          caller in a parseable format. 
  2) pass a drug to FreeDiams and tell FreeDiams 
          "show me everything you know about this drug" 
          Ideally, the information could be passed back to the 
          caller in a parseable format. 
  Please suggest how we can cooperate on these two things. 

• approach to drug dosage in renal failure
  • posting
  • Dosing.de

• how does FreeDiams will try to match “non-UID” drugs imported from external EMRs…
  • first solution should be:
    • all INNs must be informed
    • each INN must have
      • a fully configurated strength
      • a fully configurated route
    • With these data, FreeDiams can try to match a drug containing the exact composition required and show the drug's brand name.
  • second idea:
    • same data are needed
    • FreeDiams will create a “virtual drug” (meaning unmarketed) with the data and include it in the IA processing (using its INNs, strength and route)

• Interaction synthesis
  • heading: tested prescription (remember all tested drugs)
  • add a user global comment
  • interactions
    • grouped by risk level (headings)
    • showing in a table
      • related drugs
      • related ATC or IAM classes
      • risk
      • management
  • global interacting score ?
  • when printing allow user to add a global comment

• INN Dosage are stored using the ATC ID =⇒ on ATC table update :: wrong association

• Recalled drugs on list

• DDI dose-dependent, Duplication alerts:

  The next generation should include some new changes:
  - Database MASTER and DRUGS table should be joined as one table.
  - I have to think on some new fields in INTERACTIONS and in IAM_TREE
    * INTERACTIONS should inform on daily/weekly/monthly total dose. 
      * See for exemple: WARFARINE/ASPIRIN interaction Contraindicated or 
        Discourage association according to the total daily dose of 
        ASPIRIN prescribed. Idem for some METHOTREXATE DDI.
    * IAM_TREE should inform the DDI engine on the calculation 
      of duplicates. All *molecule* duplication should not be 
      warned (eg: LEVODOPA), idem for interacting classes 
      (like CYP450 substrats). These data should be informed 
      in FreeToolBox (code is not actually written).

• Creatinin && ClCr units

  Hallo Eric,
  
  Some time ago, I made some notes that
  
  	future versions will directly handle umol/L and mg/dL
  
  Is FreeDiams the object of any more development currently, and can it be on any roadmap soon that the units of
  
  		mg/dL
  		umol/L
  
  	can be made to recognize and be correctly shown when the following are passed "in" ?
  
   	<Creatinine value="1.36" unit="mg/dL"/>
   	<Creatinine value="120" unit="umol/L"/>
  
  Next, can CrCl (mL/min) be auto-calculated for such parameters? The conversion factors are:
  
     	µmol/L	/ 8.4		--> mg/L 
  
     	mg/dL	x 10		--> mg/L
  
  and for CrCl (mL/min --> mL/sec) the conversion is
  
  	mL/min	x 0.0167	--> mL/s
  
  and I would remove mmol/L from the UI, since I do not think those units are anywhere used.
  
  -- Jim

• Adding command line only features

  freediams --convert prescription.xml

• SVN tidying and script updating … acc to email “About svn global_resources > sql” (July 25-26, 2010)