Standardized Protocols (SPs)

• users of FD may value to be able to refresh / update their protocols from a central database
• users to be able to keep their own personal protocols in addition to standardized
  • need a system (nomenclature, tag or column) to visually distinguish, filter?, keep them apart
• multilanguage support for the labels and any notes
• need to reference each protocol against the source of the standard
• the possibility that different countries/locales/groups could have different standardizations
  • goes to the possible value of enabling more than one database from which to choose / subscribe (asynchronous git clones?)
• is one standardized dosage (or even drug) better than another? how to manage?

What should a protocol label, and structure, and function look like?

• can we have a standard for something that does not have an INN? I suspect that something that lacks an INN may have insufficient data to be able to even decide a standard, except maybe drugs that are new. I am not sure whether a drug might obtain an INN in one language before it obtains an INN in the other languages. I don't know if FD should presume to create a pseudo-INN for such drugs (maybe FD_temporaryINN-en, FD_temporaryINN-fr etc.?)

• below, when I write “label” what I mean is the “Protocol name” as it appears presently in FD

• we maybe do not need to have the drug name (INN) itself as part of the label, because the protocols are only presently viewed *inside* a matching drug which (for an INN) shares the INN and strength

• many (but not all) drugs need different dosages for different indications (conditions, diagnoses, purposes), therefore the label will often need something of the indication in the label

• where an indication is for chronic disease management, it maybe warrants a default of one month duration and – in this situation of chronic disease – maybe needs no duration in the label EXCEPT it is possible that drug safety or effectiveness might be important to check earlier than one month so in this case it is maybe important to include in the label something like x 10d trial but where the drug is not for chronic disease, and instead something with a time-limited protocol (acute gout; infections) or with a cycle (oral contraception; biphosphonates for bone disease; chemotherapies) this maybe –in addition to the indication– needs something about the duration in the protocol?

Later, we could have the idea of searching across drugs, based on the disease(s) and conditions and in this kind of search, the drugs eligible for the condition would be listed HOWEVER each drug that had contraindications for age or renal function etc might be able to be shown visually. Later we can ALSO have the idea whether to build standardized templates (but first we would need to be happy with protocols which are each for 1 drug only)…